Papers consist of letters, reports, addresses and lectures, relating to biological chemistry and other scientific topics, the Rockefeller Institute for Medical Research, refugee scientists, professional associations, etc.

This collection contains correspondence, drafts of papers, the manuscript of an unpublished book, and photographs. Osterhout's interest in the electrophysiology of plants is documented, as well as his professional career at the University of California, Berkeley; Harvard University; and the Rockefeller Institute.

William Jacob Robbins (1890-1978, APS 1941) was a botanist and physiologist. From 1937 to 1957 he was director of the New York Botanical Garden. His research focused on culture methods of plants in relation to biochemistry and nutrition, especially on the synthetic abilities of fungi. His studies paralleled the scientific agenda of the Rockefeller Foundation, an agency with which he was closely associated for years as adviser and trustee. He was perhaps the most influential botanist in the National Academy of Sciences (NAS) during the early postwar era, and a principal participant in the plans for the global reconstruction of science. Robbins served as president of the American Philosophical Society from 1956 to 1959.

The collection represents the data that Roe (Mrs. George Gaylord Simpson) collected on 64 scientists for her 1953 book, The Making of a Scientist. The material for each scientist includes transcripts of interviews, Rorschach and Thematic Apperception Tests, personal data, reprints of the scientist's publications, and letters several years afterward the interview asking for additional information. There are also photostats of letters and notes by the scientists dating earlier than 1949; holders of the originals of these letters is unknown.